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January 6, 2026BMC MicrobiologyOpen Access

Comparative core-genome MLST of vancomycin-resistant Enterococcus faecium supports the utility of wastewater-based surveillance: a pilot study

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Authors

AIAl-Mustapha Ahmad IbrahimLLLaura LindholmRLRiikka Laukkanen‐Ninios

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Overview

Pilot study shows wastewater-based surveillance detects antibiotic-resistant Enterococcus faecium, indicating potential for AMR monitoring.

Key Points

  • Assess the effectiveness of wastewater-based surveillance for monitoring vancomycin-resistant Enterococcus faecium.
  • Isolated VREfm from 77 wastewater samples using CHROMAgar VRE
  • Conducted antibiotic susceptibility testing using broth microdilution assay
  • Used core genome MLST to analyze genetic relatedness of isolates
  • 22% isolation rate of VREfm from wastewater samples
  • All isolates resistant to multiple antibiotics, including vancomycin
  • Majority of wastewater strains closely related to human surveillance isolates

Cite This Study

Ibrahim et al. (2026) studied this question.

synapsesocial.com/papers/695d85413483e917927a4302https://doi.org/10.1186/s12866-025-04610-3
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Surveillance and Characterization of Vancomycin-Resistant and Vancomycin-Variable Enterococci in a Hospital Setting2025
  2. 2Genomic Epidemiology of Vancomycin-Resistant Enterococcus faecium Isolates with Full and Truncated vanA Operons from Russian Hospitals2025
  3. 3Virulence signature of the endemic vancomycin-resistant <i>Enterococcus faecium</i> clones in Denmark, 2015-20232025
  4. 4Molecular characterization of vancomycin-resistant Enterococcus faecium and identification of a clinical strain co-harboring the G2505A mutation associated with linezolid resistance from a tertiary hospital in China2026
  5. 5Genomic sequencing surveillance of patients colonized with vancomycin-resistant enterococci improves detection of healthcare-associated transmission2025