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September 10, 2025AntibioticsOpen Access

Surveillance and Characterization of Vancomycin-Resistant and Vancomycin-Variable Enterococci in a Hospital Setting

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Authors

CRClaudia RotondoVAValentina AntonelliARAlberto Rossi

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Overview

Point prevalence survey assessed colonization of VRE and VVE in hospitalized patients, indicating urgent infection control measures.

Key Points

  • Of 160 rectal swabs, 54 (33.7%) were positive for vancomycin-resistant genes, showing high colonization rates.
  • Culture methods identified 47 positives, highlighting E. faecium as the most prevalent organism among antibiotic-resistant enterococci.
  • Whole-genome sequencing revealed seven clusters of E. faecium, with the most common sequence type found being ST 80.
  • Findings emphasize the need for effective infection control in healthcare settings to prevent the spread of VRE and VVE.

Cite This Study

Rotondo et al. (2025) studied this question.

synapsesocial.com/papers/68c241efb210217d647a1289https://doi.org/10.3390/antibiotics14080795
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Critical genomic insights into vancomycin-resistant <i>Enterococcus faecium</i> in Lebanon2025
  2. 2High-Resolution Genomic and Molecular Characterization of Vancomycin-Resistant Enterococci from Hospitalized Patients in a Tertiary Care Center in Riyadh, Saudi Arabia2025
  3. 3Virulence signature of the endemic vancomycin-resistant <i>Enterococcus faecium</i> clones in Denmark, 2015-20232025
  4. 4Molecular characterization of vancomycin-resistant Enterococcus faecium and identification of a clinical strain co-harboring the G2505A mutation associated with linezolid resistance from a tertiary hospital in China2026
  5. 5Genomic sequencing surveillance of patients colonized with vancomycin-resistant enterococci improves detection of healthcare-associated transmission2025