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December 16, 2025Clinical and Applied Thrombosis/HemostasisOpen Access

miR-3150b-3p Promotes Vascular Smooth Muscle Cell Injury by Targeting ARL5B

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Authors

WWWei WangRLRuirui LiangWWWeimin Wang

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Overview

Observational analysis revealed elevated miR-3150b-3p levels in coronary heart disease, indicating its diagnostic value and role in oxidative stress.

Key Points

  • Elevated levels of miR-3150b-3p are linked to increased oxidative stress in coronary heart disease patients, prompting further investigation.
  • The diagnostic value of miR-3150b-3p was confirmed via ROC curve analysis, providing critical correlations with disease severity.
  • In vitro experiments utilized ox-LDL to induce oxidative stress, measured through malondialdehyde and superoxide dismutase levels.
  • Findings suggest that miR-3150b-3p is a potential therapeutic target for managing coronary heart disease-related injury.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/6940aca13507a57a7f7a3d37https://doi.org/10.1177/10760296251399647
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