Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
December 4, 2025Molecular Nutrition & Food ResearchOpen Access

Antiobesity Efficacy of Marine Tapra Fish ( Opisthopterus tardoore ) Oil in High‐Fat Diet‐Induced Obese Mice by Activating Lipolysis and Suppressing Adipose Inflammation

View Full Paper
Ask AI
Bookmark
Share

Authors

RKRiya KarMPManisha PhoujdarSPShrabani Pradhan

Discussion

Loading...

Member takes

Overview

Experiment shows antiobesity effects and reduced adipose inflammation in obese mice with Opisthopterus tardoore oil, highlighting potential treatment benefits.

Key Points

  • Body weight and adipocyte size significantly reduced in mice given Opisthopterus tardoore oil for four weeks, supporting its efficacy against obesity.
  • Treatment increased levels of beneficial adiponectin and decreased proinflammatory cytokines, specifically interleukin-1 receptor antagonist and IL-6.
  • Analysis of mice fed a high-fat diet revealed the oil's role in managing obesity by modulating lipogenic and inflammatory pathways.
  • This research may enable novel antiobesity therapies through marine-derived interventions, calling for further studies on dosage and application.

Cite This Study

Kar et al. (2025) studied this question.

synapsesocial.com/papers/6930dc8aea1aef094cca2850https://doi.org/10.1002/mnfr.70341
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Fish Oil Present in High-Fat Diet, Unlike Other Fats, Attenuates Oxidative Stress and Activates Autophagy in Murine Adipose Tissue2025
  2. 2Anti-Obesity and Hepatoprotective Effects of Herring–Saury Oil Fermented by Lactobacillus brevis KCCM13538P in High-Fat-Diet-Induced Mice2025
  3. 3Muscle Strength, Lipid Metabolism and Hepatic Steatosis Are Improved with Ursolic Acid Treatment in High-Fat Diet-Induced Obese Mice2025 · 1 citations
  4. 4Tamarind-Derived Trypsin Inhibitor as a Potential Therapeutic Agent for Obesity: Evidence from In Vitro and Zebrafish Models2025
  5. 5Extra virgin olive oil supplementation reduces inflammation in the arcuate nucleus of the hypothalamus and improves metabolic parameters in obese rats.2025