Extra virgin olive oil supplementation reduces inflammation in the arcuate nucleus of the hypothalamus and improves metabolic parameters in obese rats.
Supplementation with extra virgin olive oil improves metabolic parameters and reduces hypothalamic inflammation in obese rats, suggesting a potential therapeutic strategy.
Key Points
EVOO supplementation reduced inflammation markers in the arcuate nucleus of the hypothalamus, improving metabolic outcomes.
Chronic high-fat diet induced obesity led to increased body weight and fasting glucose levels, which EVOO countered.
Adult Wistar rats on a high-fat diet showed impaired satiety, which was improved with extra virgin olive oil supplementation.
Results support EVOO as a promising nutritional strategy for restoring metabolic health by reducing hypothalamic inflammation.