Synapse
⌘+K
Synapse
PulseExploreJournal ClubResearchersJournals
Instagram
HomeJournal ClubExplore
November 4, 2025Combinatorial Chemistry & High Throughput Screening

LINC00888 Promotes Gastric Cancer Growth and Metastasis by Sponging miR-145-5p to Regulate FZD7 Expression

View Full Paper
Ask AI
Bookmark
Share

Authors

XZXuemei ZhouAZA.H. ZhangSMSuo Mo

Discussion

Loading...

Member takes

Overview

Analysis shows LINC00888 promotes cancer progression in gastric cancer, suggesting it as a potential therapeutic target and prognostic biomarker.

Key Points

  • LINC00888 promotes gastric cancer progression, influencing the miR-145-5p/FZD7 axis.
  • Upregulation of LINC00888 correlates with advanced stage and recurrence in gastric cancer patients.
  • Bioinformatics analyses and experimental validation employed to assess molecular functions involving LINC00888.
  • Integrating LINC00888 as a biomarker may enhance personalized management in gastric cancer treatment.

Cite This Study

Zhou et al. (2025) studied this question.

synapsesocial.com/papers/690945348f2297dc13532ff2https://doi.org/10.2174/0113862073431030251019092839
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Long Intergenic Non-coding RNA — LINC00659 — Expression Changes in Gastric Cancer: Lessons from Northwestern Iran2025
  2. 2Super-enhancer-associated LINC00963 promotes metastasis of gastric cancer through epithelial-mesenchymal transition2025
  3. 3LINC01106 Stimulates Growth And Metastasis Of Colorectal Carcinoma By Sponging MiR-744-5p2025
  4. 4The Emerging Landscape of LINC01123 in Cancer: Roles, Mechanisms, and Clinical Significance2025
  5. 5The Role of the TIMP1/LINC01615 Axis as a Regulator of the EMT Pathway in Gastric Cancer2025