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January 1, 2025Pakistan Journal of Pharmaceutical Sciences

LINC01106 Stimulates Growth And Metastasis Of Colorectal Carcinoma By Sponging MiR-744-5p

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Authors

GWGenxia WeiBLBo LiuYGYu Guo

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Overview

Functional assays demonstrate that linc01106 boosts proliferation and metastasis in colorectal carcinoma, suggesting miR-744-5p involvement.

Key Points

  • LINC01106 significantly promotes proliferation and metastasis of colorectal carcinoma cells.
  • Knockdown of LINC01106 led to reduced proliferation and metastatic capabilities in cancer cells.
  • Observational analysis using clinical specimens revealed LINC01106's high expression correlates with poor survival in patients.
  • Further research is needed to establish LINC01106 as a therapeutic target for enhancing colorectal cancer treatment.

Cite This Study

Wei et al. (2025) studied this question.

synapsesocial.com/papers/68af2683cf1dd9ea359e1945https://doi.org/10.36721/pjps.2025.38.4.reg.13786.1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Emerging Landscape of LINC01123 in Cancer: Roles, Mechanisms, and Clinical Significance2025
  2. 2Inhibition of Linc00284 Enhances Radiosensitivity in Colorectal Cancer Through miR‐559/c‐Myc Axis2025
  3. 3The Good, the Bad, or Both? Unveiling the Molecular Functions of LINC01133 in Tumors2025
  4. 4LINC00888 Promotes Gastric Cancer Growth and Metastasis by Sponging miR-145-5p to Regulate FZD7 Expression2025
  5. 5Linc01232 regulates mir-516a-5p/bcl9 axis to promote triple-negative breast cancer progression2025