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August 18, 2025Biological Procedures OnlineOpen Access

The Role of the TIMP1/LINC01615 Axis as a Regulator of the EMT Pathway in Gastric Cancer

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Authors

JLJiying LiuYOYeganeh OlyaeeKMKhatere Mokhtari

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Overview

Assessment of TIMP1 and LINC01615 identifies their roles in the EMT pathway as potential biomarkers in gastric cancer.

Key Points

  • TIMPI and LINC01615 signal high correlation enhancing gastric cancer progression and invasion, suggesting therapeutic opportunities.
  • Differential expression analysis found 2,926 genes with 87 linked to the EMT pathway, highlighting key molecular interactions.
  • Correlation analysis confirmed TIMP1 and LINC01615 upregulation in tumor tissues using RT-qPCR among 50 samples, emphasizing their roles.
  • The study suggests that targeting the TIMP1/LINC01615 axis may enhance treatment outcomes for gastric cancer.

Cite This Study

Liu et al. (2025) studied this question.

synapsesocial.com/papers/68c237aeb210217d647765bfhttps://doi.org/10.1186/s12575-025-00297-y
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