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October 30, 2025Pakistan Journal of Medical & Health Sciences

Integrated Public Health Evaluation of Gut Microbiota, Inflammatory Biomarkers, and Nutritional Status in Patients Undergoing Colorectal Cancer Surgery

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Authors

ARAdnan ur RehmanMTManal TariqFRFatima Rashid

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Overview

Prospective observational study finds gut dysbiosis and low albumin predict complications in colorectal cancer surgery, suggesting nutritional optimization may enhance recovery.

Key Points

  • Patients experiencing gut dysbiosis showed significantly higher levels of inflammatory biomarkers such as IL-6.
  • Research identified hypoalbuminemia as a key predictor of postoperative complications and longer hospital stays.
  • A prospective observational study included 100 colorectal cancer patients undergoing elective surgery assessed for various predictors.
  • This integrated analysis highlights the importance of microbiota balance and nutrition in improving surgical outcomes for colorectal cancer patients.

Cite This Study

Rehman et al. (2023) studied this question.

synapsesocial.com/papers/6902ac506303672991d2d253https://doi.org/10.53350/pjmhs20231710366
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Role of Surgical and Perioperative Factors in Shaping Gut Microbiome Recovery After Colorectal Surgery2025 · 8 citations
  2. 2Association of Preoperative Gut Microbiota Disturbances with Postoperative Infectious Complications in Major Gastrointestinal Cancer Surgery: A Large-Scale Exploratory Study2025 · 3 citations
  3. 3Nutritional status and postoperative outcomes in patients undergoing major resection for gastrointestinal cancer: a prospective cohort study2025 · 1 citations
  4. 4The impact of enteral immunonutrition on gut microbiota in colorectal cancer and gastric cancer patients in the preoperative period—preliminary results of randomized clinical trial2025 · 7 citations
  5. 5Risk factors for postoperative abdominal infection of colorectal cancer: A systematic review based on the PRISMA guidelines2026