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September 18, 2025AIDS

Advanced HIV disease and 30-day mortality among hospitalized adults with virally suppressed HIV in South Africa

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Authors

SSSamuel J. StarkeZHZiyang HeRHRuan Hollamby

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Overview

Observational study assesses 30-day mortality rates among adults with virally suppressed HIV, highlighting the significance of advanced HIV disease and tuberculosis.

Key Points

  • 30-day mortality rate among 99 hospitalized patients with virally suppressed HIV was 12.1%, indicating a critical health concern.
  • AIDS-defining illnesses like tuberculosis accounted for 27.3% of hospitalizations, marking it a significant health challenge.
  • Conducted as a prospective observational study at a public tertiary hospital in Klerksdorp, South Africa, from October 2023 to September 2024.
  • Findings underscore the urgent need to enhance early TB detection and post-discharge care for individuals living with HIV.

Cite This Study

Starke et al. (2025) studied this question.

synapsesocial.com/papers/68d435d6713b0b5dfea751d6https://doi.org/10.1097/qad.0000000000004336
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Also Consider

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  1. 1Characteristics of Individuals with Advanced HIV Disease and Risk Factors for Mortality in a Contemporary Cohort in South Africa2025 · 1 citations
  2. 2Characteristics and six-month viral load suppression of clients presenting with advanced HIV disease in South Africa2025
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  4. 4Ten-year outcomes of antiretroviral therapy: a retrospective cohort study in Tshwane district, South Africa2025
  5. 5Comorbidity Clusters and Immune Profiles in Hospitalized People with HIV: A Retrospective Analysis at a Tertiary Care Center in Eastern China2025