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September 16, 2025Infection and Drug ResistanceOpen Access

Comorbidity Clusters and Immune Profiles in Hospitalized People with HIV: A Retrospective Analysis at a Tertiary Care Center in Eastern China

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Authors

ZWZhikai WanKWKun WangLHLingling He

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Overview

Retrospective analysis highlights key comorbidities in HIV patients and their immune profiles.

Key Points

  • NADs are now the leading cause of hospitalization among people with HIV.
  • Patients with opportunistic infections had a shorter duration since HIV diagnosis compared to other groups.
  • The CD4/CD8 ratio below 0.5 was independently associated with AIDS-defining malignancies.
  • Immunological analysis showed differences in CD4+ T cell counts based on comorbidity groups.

Cite This Study

Wan et al. (2025) studied this question.

synapsesocial.com/papers/68d43c79713b0b5dfea7bb9chttps://doi.org/10.2147/idr.s538627
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Regional inequalities in comorbidity patterns among aging HIV populations in China: tales of two cities with distinct HIV dynamics2025
  2. 2Advanced HIV disease and 30-day mortality among hospitalized adults with virally suppressed HIV in South Africa2025
  3. 3Cancer Prevention Pathways in People Living with HIV: Assessment of Prevalence and Related Factors Among Individuals Attending HIV Division of Ferrara Hospital2025
  4. 4A national, multicenter, retrospective study of human immunodeficiency virus infection-associated lymphoma in China2025 · 2 citations
  5. 5Two-threshold defined immune non-responders are associated with long-term morbidity in people with HIV: a prospective cohort study2025