White Matter Integrity and Asymmetry Alterations in Young Children with Autism Spectrum Disorder: An Automated Fiber Quantification Study

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Automated fiber quantification reveals white matter abnormalities linked to behavior in children with ASD.

Children with autism spectrum disorder show altered white matter microstructure, impacting behavioral symptoms.
Diffusion tensor imaging identified significant white matter abnormalities in 36 children with ASD compared to 27 controls.
Automated fiber quantification analyzed white matter tract diffusion metrics to assess microstructural integrity.
Findings suggest that white matter biomarkers can aid in the early diagnosis and targeted intervention for autism.

Luo et al. (2025) studied this question.

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