September 25, 2025Open Access

Widespread alterations in white matter microstructure in autism: A multilevel meta-analysis

View Full Paper

Ask AI

Bookmark

Authors

CYChristy D. Yoon AAAndrew L. AlexanderUniversity of Wisconsin–Madison BTBrittany G. Travers

Discussion

Member takes

Implication

Meta-analysis reveals significant differences in white matter microstructure between ASD and TD individuals, suggesting implications for brain connectivity.

Key Points

Individuals with ASD show lower fractional anisotropy in critical white matter tracts, indicating reduced microstructural integrity,
The study identified a moderate summary effect size for FA in eight tracts, highlighting significant structural differences,
Using a multilevel meta-analysis framework, this research analyzed 680 effect sizes from 59 studies focusing on ASD,
Findings suggest a need to consider age and sex when generalizing results, given limitations in participant demographics.

Cite This Study

Yoon et al. (2025) studied this question.

synapsesocial.com/papers/68d5bd64dc445aa9033b02a5 https://doi.org/10.21203/rs.3.rs-7411531/v1

View Full Paper

Ask AI

Bookmark

Implication

Meta-analysis reveals significant differences in white matter microstructure between ASD and TD individuals, suggesting implications for brain connectivity.

Widespread alterations in white matter microstructure in autism: A multilevel meta-analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

Widespread alterations in white matter microstructure in autism: A multilevel meta-analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider