August 6, 2025Brain SciencesOpen Access

Exploring the Autistic Brain: A Systematic Review of Diffusion Tensor Imaging Studies on Neural Connectivity in Autism Spectrum Disorder

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Discussion

Systematic review highlights altered neural connectivity in adults with autism spectrum disorder, suggesting changes in white matter structure.

Autism spectrum disorder shows unique white matter alterations in adults, differing from children.
Key metrics like fractional anisotropy and mean diffusivity indicate specific structural differences.
Review analyzed 26 studies focusing on adult ASD, emphasizing regional diversity in white matter findings.
Findings suggest potential adaptations in brain structure in adults with ASD during maturation.

Marano et al. (2025) studied this question.

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Systematic review highlights altered neural connectivity in adults with autism spectrum disorder, suggesting changes in white matter structure.