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September 10, 2025Journal of the American Heart AssociationOpen Access

Phenotypes of Hypertension: Impact of Age and Sex on Hemodynamic Mechanisms

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Authors

DCDomonkos CsehYYYasmin YasminBMBarry J. McDonnell

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Overview

Cross-sectional analysis reveals distinct hemodynamic patterns in hypertension, highlighting age and sex variations.

Key Points

  • Isolated systolic hypertension was most prevalent in young men, with elevated cardiac output and stroke volume.
  • In younger females, systolic diastolic hypertension was common, linked to increased peripheral vascular resistance (PVR).
  • The study involved cross-sectional analysis of 5371 individuals across various age and sex groups.
  • Targeting primary hemodynamic abnormalities may lead to more effective treatments for essential hypertension.

Cite This Study

Cseh et al. (2025) studied this question.

synapsesocial.com/papers/68c243acb210217d647a888ehttps://doi.org/10.1161/jaha.125.042096
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