Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 10, 2025AntioxidantsOpen Access

Abelmoschus esculentus Ameliorates Cognitive Impairment in Hyperlipidemic ApoE−/− Mice via Modulation of Oxidative Stress and Neuronal Differentiation

View Full Paper
Ask AI
Bookmark
Share

Authors

CPChiung-Huei PengHLHsin-Wen LiangCWChau-Jong Wang

Discussion

Loading...

Member takes

Overview

Observational analysis found that abelmoschus esculentus improves cognitive function in apoE−/− mice, suggesting a role in reducing oxidative stress and enhancing neuronal differentiation.

Key Points

  • Abelmoschus esculentus significantly improved cognitive and memory function in hyperlipidemic apoE−/− mice.
  • The study revealed a reduction in serum LDL-C and triglycerides, indicating a positive effect on metabolic health.
  • Neuronal differentiation was enhanced in vitro with the administration of abelmoschus esculentus in glucose and palmitate-stressed cells.
  • These findings imply that abelmoschus esculentus may offer therapeutic benefits for cognitive decline related to oxidative stress.

Cite This Study

Peng et al. (2025) studied this question.

synapsesocial.com/papers/68c241efb210217d647a1f61https://doi.org/10.3390/antiox14080955
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1An Acebuche Oil-Enriched Diet Prevents Early-Stage Cerebrovascular Alterations in the 5xFAD Mouse Model of Alzheimer’s Disease2026
  2. 2Standardized <i>Artemisia argyi</i> Extract Alleviates Scopolamine-Induced Memory Impairment in Mice2026
  3. 3Effect of Hyperbaric Oxygen Treatment on Lipid Metabolism and Neurovascular Microenvironment in an Apolipoprotein E Knockout Mouse Model2025
  4. 4Tithonia diversifolia (Hemsl.) extract attenuates cognitive dysfunction, oxidative stress and neuroinflammation in a model of sporadic Alzheimer’s disease induced by streptozotocin2025
  5. 5Avenanthramide-C Mitigates High-Fat Diet-Accelerated Alzheimer’s Pathologies via NOD1-Driven Neuroinflammation in 5×FAD Mice2025