Tithonia diversifolia (Hemsl.) extract attenuates cognitive dysfunction, oxidative stress and neuroinflammation in a model of sporadic Alzheimer’s disease induced by streptozotocin
Experimental analysis shows Tithonia diversifolia extract improves cognitive function in Alzheimer's disease mice, suggesting potential as a neuroprotective agent.
Key Points
EETD reduced cognitive dysfunction and emotional distress in a streptozotocin-induced Alzheimer's model, highlighting its therapeutic potential.
The extract increased antioxidant defenses and decreased neuroinflammation markers, supporting its role in cognitive health.
Behavioral tests indicated significant improvements in memory and anxiety following EETD treatment, correlating with biochemical findings.
Further identification of specific phytoconstituents in Tithonia diversifolia could advance therapeutic strategies for Alzheimer's disease.