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September 10, 2025Acta Facultatis Medicae NaissensisOpen Access

Vascularization, proliferative activity and the p53 status in glioblastomas

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Authors

DTDesanka TasićIDIrena DimovMKMiloš Kostov

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Overview

Observational analysis reveals no significant links between vascularization and p53 status in glioblastomas.

Key Points

  • No significant association was detected between microvessel density and p53 status in glioblastomas.
  • High microvessel density was linked to increased proliferative activity, but not statistically significant.
  • Tissue samples from 100 primary glioblastomas were analyzed using immunohistochemistry techniques.
  • The findings suggest p53 may not impact vascularization in glioblastomas, indicating possible other influencing factors.

Cite This Study

Tasić et al. (2025) studied this question.

synapsesocial.com/papers/68c2409bb210217d6479b33ehttps://doi.org/10.5937/afmnai42-54582
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