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September 25, 2025

The effects of dysregulated ion channels and vasoconstriction in glioblastoma multiforme

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Authors

RMRohit MaheshNMNitya Mahesh

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Overview

Research shows vasoconstriction and ion channel dysfunction contribute to glioblastoma growth, indicating potential therapeutic targets.

Key Points

  • Vasoconstriction may accelerate glioblastoma growth by blocking blood flow and nutrient delivery.
  • Analysis revealed an enriched GABA signaling pathway and depleted n-VGCC and NMDA pathways in glioblastoma patients.
  • Literature searches and gene expression analysis provided insights into underlying mechanisms of glioblastoma.
  • Findings suggest significant implications for potential treatments targeting blood vessel regulation in glioblastoma.

Cite This Study

Mahesh et al. (2025) studied this question.

synapsesocial.com/papers/68d5e205bd7882ccb9b8685chttps://doi.org/10.59720/23-187
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