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September 10, 2025Journal of Saidu Medical College Swat

Early Prediction of Post-Cardiac-Surgery Acute Kidney Injury: Urinary NGAL versus Serum Creatinine

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Authors

LSLubna SarfrazAIAnum IftikharSRSara Reza

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Overview

Descriptive cross-sectional study compares urinary NGAL and serum creatinine for diagnosing AKI, suggesting NGAL's superior sensitivity and specificity.

Key Points

  • Urinary NGAL demonstrated superior diagnostic accuracy for AKI with 92% sensitivity and 81.25% specificity.
  • Compared to serum creatinine, NGAL had a positive predictive value of 88.46% and negative predictive value of 86.67%.
  • A descriptive cross-sectional study included 123 cardiac surgery patients assessing biomarker performance postoperatively.
  • Findings suggest incorporating urinary NGAL could improve early detection of AKI in clinical settings.

Cite This Study

Sarfraz et al. (2025) studied this question.

synapsesocial.com/papers/68c2404eb210217d6479a9e9https://doi.org/10.52206/jsmc.2025.15.3.1066
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A-100 The evaluation of kidney injury molecule and neutrophil gelatinase associated lipocalin as predictive biomarkers of acute kidney injury in a subset of Jamaican patients undergoing cardiopulmonary bypass surgery2025
  2. 2Diagnostic utility of urinary neutrophil gelatinase associated lipocalin (µNGAL) in predicting the severity of acute kidney injury2025 · 1 citations
  3. 3Plasma neutrophil gelatinase-associated lipocalin protein and cystatin C as predictive biomarkers for acute kidney injury following cardiopulmonary bypass surgery: a prospective study2025 · 1 citations
  4. 4Changes in Serum Neutrophil Gelatinase-Associated Lipocalin (NGAL) and Their Relationship with Kidney Function in Different Stages of Chronic Kidney Disease2025
  5. 5Clinical Implementation of Urinary Neutrophil Gelatinase-Associated Lipocalin Testing for Diagnosing Acute Kidney Injury in an Academic Tertiary Care Medical Centre2025 · 4 citations