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October 1, 2025Journal of Indira Gandhi Institute Of Medical SciencesOpen Access

Diagnostic utility of urinary neutrophil gelatinase associated lipocalin (µNGAL) in predicting the severity of acute kidney injury

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Authors

JAJony AgarwalABArchana BajpayeePAPuneeth Babu Anne

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Overview

Prospective cohort study finds uNGAL predicts renal recovery better than serum creatinine, suggesting diagnostic potential.

Key Points

  • Higher uNGAL levels indicate more severe acute kidney injury, enhancing predictive ability.
  • uNGAL has a sensitivity of 84% and specificity of 63% in predicting acute kidney injury severity.
  • This prospective cohort study shows uNGAL is superior to serum creatinine in predicting renal recovery.
  • Urine NGAL concentration correlates with recovery, particularly in younger and female patients.

Cite This Study

Agarwal et al. (2025) studied this question.

synapsesocial.com/papers/68dd91cbfe798ba2fc4989fbhttps://doi.org/10.4103/jigims.jigims_39_25
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinical Implementation of Urinary NGAL Testing for Diagnosing Acute Kidney Injury in an Academic Tertiary Care Medical Centre2025
  2. 2Early Prediction of Post-Cardiac-Surgery Acute Kidney Injury: Urinary NGAL versus Serum Creatinine2025
  3. 3Assessing neutrophil gelatinase-associated lipocalin as an early indicator for AKI among gastroenteritis patients with dehydration2025
  4. 4Changes in Serum Neutrophil Gelatinase-Associated Lipocalin (NGAL) and Their Relationship with Kidney Function in Different Stages of Chronic Kidney Disease2025
  5. 5Urinary Neutrophil Gelatinase-Associated Lipocalin and Serum Cystatin C as Early Biomarkers of Acute Kidney Injury in Critically Ill Children: Single-Center PICU Cohort, 2024–20252026