Plasma neutrophil gelatinase-associated lipocalin protein and cystatin C as predictive biomarkers for acute kidney injury following cardiopulmonary bypass surgery: a prospective study
Prospective study reveals plasma NGAL and cystatin C as promising predictive biomarkers for acute kidney injury risk after cardiopulmonary bypass surgery.
Key Points
Elevated plasma levels of NGAL and CysC significantly predict acute kidney injury after cardiopulmonary bypass surgery.
The area under the curve for plasma CysC was 0.77 at both 12 and 36 hours, showing strong predictive capacity.
Binary logistic regression identified multiple risk factors for postoperative acute kidney injury in 95 patients.
Findings may facilitate earlier identification of patients at high risk for acute kidney injury post-surgery.