Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 10, 2025Russian Journal of Pediatric Hematology and OncologyOpen Access

Complex endoscopic diagnosis of the gastrointestinal form of acute graft-versus-host disease in children who underwent allogeneic hematopoietic stem cell transplantation. Single-center study

View Full Paper
Ask AI
Bookmark
Share

Authors

VLV. V. LozovayaOGO. A. GusarovaИКИ. О. Костарева

Discussion

Loading...

Member takes

Overview

Retrospective study finds comprehensive endoscopic examination improves diagnostic accuracy for GI aGVHD, suggesting better outcomes for pediatric patients.

Key Points

  • A comprehensive endoscopic examination confirmed GI aGVHD in 81.5% of suspected cases.
  • The diagnostic value of forceps biopsy for altered mucosa in GI aGVHD was 86.4%.
  • Sensitivity of combined endoscopic methods reached 88.9%, compared to 68.5% for colonoscopy alone.
  • Utilizing a comprehensive approach improves diagnosis, reinforcing the need for thorough examinations in suspected cases.

Cite This Study

Lozovaya et al. (2025) studied this question.

synapsesocial.com/papers/68c23e02b210217d6478fdbdhttps://doi.org/10.21682/2311-1267-2024-11-4-60-70
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Stage 0+ lower gastrointestinal (LGI) acute graft-versus-host disease (aGVHD) is associated with high response to non-systemic treatment, low incidence of moderate to severe chronic graft-versus-host disease (cGVHD) and low non-relapse mortality (NRM)2025
  2. 2Microbiome Signature Linked to the Development and Management of Intestinal Acute Graft-versus-Host Disease in Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation2025
  3. 3Disruption of intestinal homeostasis reflected by DAO and microbiota alterations in gvhd post-HSCT.2025
  4. 4A multi-timepoint immune profiling model for differentiating gvhd- and infection-associated diarrhea following allo-HSCT2025
  5. 5Expanding Role of Gastroenterologists in Acute Gastrointestinal Graft-versus-Host Disease: From Diagnosis and Management to Microbiome-Based Strategies2025