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December 8, 2025BloodOpen Access

A multi-timepoint immune profiling model for differentiating gvhd- and infection-associated diarrhea following allo-HSCT

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Authors

MCMan ChenWZWei ZhaoHWHui Wang

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Overview

Analysis reveals distinct immune profiles in GVHD and infection-related diarrhea post-allo-HSCT, suggesting a predictive model may enhance clinical decisions.

Key Points

  • Diarrhea differentiation relies on immune profiling, enhancing clinical diagnosis and treatment strategies.
  • Higher cytokine levels characterize GVHD-associated diarrhea, aiding in early diagnosis.
  • Endoscopic evaluation with histopathology assists in confirming the diagnosis of diarrhea causes post-transplant.
  • The predictive model enables improved decision-making for treatment of diarrhea post-allo-HSCT.

Cite This Study

Chen et al. (2025) studied this question.

synapsesocial.com/papers/69362f694fa91c937236deffhttps://doi.org/10.1182/blood-2025-4231
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