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August 17, 2025Proceedings of The Nutrition Society

Human milk bioactive compounds and allergic and infectious immunological outcomes: A systematic review

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Authors

EVEduard Flores VenturaDGDaria GusevaRERegina Ensenauer

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Overview

Systematic review highlights human milk's bioactive compounds protecting against allergies and infections in infants.

Key Points

  • Human milk bioactive compounds may reduce allergic and autoimmune conditions in infants, suggesting protective effects.
  • Thirty-two studies involving 7,888 mother-infant pairs found that specific fatty acids in human milk are linked to lower allergy rates.
  • Observational analysis focused on bioactive compounds in human milk and their influence on various immunological outcomes in infants.
  • These findings may inform strategies for preventing infections and allergies, underscoring the importance of breastfeeding.

Cite This Study

Ventura et al. (2025) studied this question.

synapsesocial.com/papers/68c236b2b210217d64775425https://doi.org/10.1017/s0029665125100712
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effects of maternal allergy and supplementation with ω‐3 fatty acid and probiotic on human milk oligosaccharides2025
  2. 2A-358 Comparison of Immunoregulatory miRNA, Human Milk oligosaccharides (HMO’s) and Gut Microbiomes between Infants Fed with Human Breast Milk Versus Infant Formula2025
  3. 3Characterization of 2025
  4. 4Exposure to maternal human milk components interacts with infant polygenic risk to predict childhood atopy2025
  5. 5Host and environmental determinants of human milk oligosaccharides and microbiota in the Lifelines NEXT cohort2025