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September 10, 2025Pediatric Allergy and ImmunologyOpen Access

Effects of maternal allergy and supplementation with ω‐3 fatty acid and probiotic on human milk oligosaccharides

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Authors

AAAhmed Al‐KaabawiELEva LandbergMMMagalí Martí

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Overview

Observational study reveals maternal allergy and ω-3 fatty acid affect human milk oligosaccharides, suggesting implications for infant health.

Key Points

  • Maternal supplementation with ω‐3 fatty acid decreased HMO diversity during lactation.
  • Allergic mothers exhibited significantly lower levels of several HMOs compared to non-allergic mothers.
  • A positive correlation was found between SIgA and fucosylated HMOs, while a negative correlation was seen with sialylated HMOs.
  • Milk samples were collected in a clinical trial to measure the impact of maternal factors on HMO levels.

Cite This Study

Al‐Kaabawi et al. (2025) studied this question.

synapsesocial.com/papers/68c23f1fb210217d64794efdhttps://doi.org/10.1111/pai.70162
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Human milk bioactive compounds and allergic and infectious immunological outcomes: A systematic review2025
  2. 2The Developmental Trajectory and Correlation of Human Milk Microbiota and Oligosaccharides in Taiwanese Lactating Mothers.2025
  3. 3Host and environmental determinants of human milk oligosaccharides and microbiota in the Lifelines NEXT cohort2025
  4. 4Human milk oligosaccharides and infant gut microbiome in Mongolian mother-infant dyads2025 · 3 citations
  5. 5A review of human milk oligosaccharide concentrations of breast milk for infants and young children through 24 months of age2025