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August 17, 2025BioMed Research InternationalOpen Access

Impact of Fructose‐Enhanced Solid and Soft Drink Diets on Metabolism, Physiology, and Gut Microbiome in Pregnant Rats

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Authors

XHXiaoyuan HanLSLinda D. ShortliffeNKNeeraja Kambham

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Overview

Observational analysis reveals high-fructose diets altered metabolism and gut microbiome in pregnant rats, suggesting implications for maternal health.

Key Points

  • Pregnant rats on high-fructose diets showed increased carbohydrate intake while decreasing protein and fat consumption, indicating diet-driven changes.
  • The soft drink group had nearly double the fluid intake and urinary output at midpregnancy, revealing significant dietary effects during pregnancy.
  • Analysis included body weight, blood pressure, and fasting blood glucose measures among pregnant rats across three diet groups to ascertain metabolic shifts.
  • Pregnancy-related dyslipidemia was observed, with distinct changes in the gut microbiome based on the fructose diet composition in the pregnant rats.

Cite This Study

Han et al. (2025) studied this question.

synapsesocial.com/papers/68c23652b210217d6477419ehttps://doi.org/10.1155/bmri/6902453
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