October 8, 2025

Advanced Quantitative Microstructure Imaging in Autism: A Review of Methodology, Group Differences, and Associations With Developmental Outcomes.

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Authors

CYChristy D. Yoon DDDouglas C. DeanUniversity of Wisconsin–Madison

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Implication

This review examines white matter microstructure in autism using advanced MRI techniques, highlighting notable differences and associations with developmental outcomes.

Key Points

Findings show consistent lower values in white matter microstructure across major regions in autism, suggesting persistent alterations related to the condition.
Across 34 reviewed studies, diffusion MRI techniques like DKI and CSD were prevalent, while MTI was the least utilized despite its potential significance.
The study of white matter integrity indicates significant associations between neuroimaging measures and cognitive, emotional, and social development outcomes.
This review adheres to PRISMA guidelines, offering comprehensive insights into methodologies and limitations impacting autism research.

Cite This Study

Yoon et al. (2025) studied this question.

synapsesocial.com/papers/68e6bc5f38ca8e474d54a088 https://doi.org/10.1002/aur.70122

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Implication

This review examines white matter microstructure in autism using advanced MRI techniques, highlighting notable differences and associations with developmental outcomes.

Advanced Quantitative Microstructure Imaging in Autism: A Review of Methodology, Group Differences, and Associations With Developmental Outcomes.

Discussion

Member takes

Implication

Key Points

Cite This Study

Advanced Quantitative Microstructure Imaging in Autism: A Review of Methodology, Group Differences, and Associations With Developmental Outcomes.

Discussion

Member takes

Implication

Key Points

Cite This Study

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