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June 13, 2026Antimicrobial Resistance and Infection ControlOpen Access

Multidrug-resistant organism carriage in Vietnamese district hospitals before and after an antimicrobial stewardship intervention

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Authors

JDJaslyn DoshiTPThai Duy PhamYPYen Ngoc Pham

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Overview

Randomized trial assesses MRO carriage in Vietnamese hospitals, suggesting modest MRSA reduction after intervention.

Key Points

  • The study aimed to estimate MRO carriage prevalence among district hospital inpatients in Vietnam and evaluate changes following AMS intervention.
  • Two repeated cross-sectional surveys conducted in four district hospitals in Vietnam (March and August 2022).
  • Six-month AMS intervention included guidelines, education, and audits.
  • Prevalence estimates compared using two-proportion tests and mixed-effects binary regression models for risk factors.
  • Prevalence of ESBL-producing Enterobacterales remained high; CPE at 2.7% and MRSA at 3%.
  • MRSA carriage decreased from 5% to 1% post-intervention (−4.0%, 95% CI -7.2%, -0.7%).
  • No change in the prevalence of ESBL-producing Enterobacterales or CPE following the intervention.

Cite This Study

Doshi et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf393faef96ed7f05607chttps://doi.org/10.1186/s13756-026-01752-5
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