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September 5, 2025Annals of Clinical Microbiology and AntimicrobialsOpen Access

The bacterial etiology and antimicrobial susceptibility of lower respiratory tract infections in Vietnam

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Authors

TDTrần Thị Ngọc DungOxford University Clinical Research UnitVCVinh ChauOxford University Clinical Research UnitPÁPhạm Hồng ÁnhNagasaki University

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Overview

This analysis shows high antimicrobial resistance patterns in major bacterial pathogens, suggesting urgent interventions. It implicates carbapenem-resistant and ceftazidime-avibactam resistant strains as serious threats.

Key Points

  • Bacterial pathogens from lower respiratory tract infections show high rates of antimicrobial resistance.
  • 94.4% of isolates were from hospital-acquired infections, with Acinetobacter baumannii being predominant.
  • Carbapenem-resistant Gram-negative pathogens were prevalent, notably resistant to ceftazidime-avibactam.
  • A strong link between antimicrobial resistance phenotype and genotype among K. pneumoniae and E. coli emphasizes the need for targeted therapies.

Cite This Study

Dung et al. (2025) studied this question.

synapsesocial.com/papers/68c23966b210217d6477bb33https://doi.org/10.1186/s12941-025-00818-3
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