Effect of antibiotic and healthcare exposure on long-term dynamics of extended-spectrum beta-lactamase producing (ESBL) Enterobacterales colonisation in Cambodian children
Clinical cohort reveals the influence of antibiotic exposure and healthcare on ESBL Enterobacterales colonisation dynamics in children, suggesting implications for AMR strategies.
Key Points
ESBL-E carriage was found to be prevalent among Cambodian children, highlighting a significant public health concern.
Kids with prior antibiotic exposure had a 40% higher chance of gaining ESBL K. pneumoniae colonisation episodes.
Healthcare exposure lowered the likelihood of losing ESBL K. pneumoniae colonisation episodes by around 30%.
The study underscores the need for targeting antibiotic and healthcare exposure to combat AMR effectively.
Cite This Study
Ardura‐Garcia et al. (2025) studied this question.