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June 12, 2026European Journal of Preventive CardiologyOpen Access

Effectiveness of comprehensive outpatient cardiac rehabilitation among heart failure patients in a developing country

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Why the study?

Does comprehensive outpatient cardiac rehabilitation improve functional capacity, cardiac function, and quality of life in patients with heart failure?

Population

53 patients with heart failure with mildly reduced ejection fraction and reduced ejection fraction, mean age…

Design

Cohort

Follow-up

upon CR completion

Authors

ANA NeelamegamPCP ChockalingamRDR Dilliraj

Discussion

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Overview

May support cardiac rehabilitation in heart failure; hypothesis-generating and requires randomized confirmation before practice change.

Key Points

  • This study aims to assess the effectiveness of comprehensive outpatient cardiac rehabilitation in improving clinical and quality of life parameters for heart failure patients.
  • Retrospective analysis of 53 heart failure patients from 2014 to 2025
  • Assessment of clinical parameters like LVEF and 6MWD using SF-12 questionnaire for QoL
  • Programs delivered by a multidisciplinary team through centre-based and home-based methods.
  • Significant improvement in 6MWD from 390±99 to 455±106 meters (p=0.0001)
  • LVEF increased from 40±5 to 47±10 (p=0.0001)
  • Quality of life improved with PCS from 37±9 to 45±6 (p=0.0052) and MCS from 47±7 to 52±7 (p=0.019).

Structured PICO

Does comprehensive outpatient cardiac rehabilitation improve functional capacity, cardiac function, and quality of life in patients with heart failure?

P
Population
53 patients with heart failure with mildly reduced ejection fraction (HFmrEF) and reduced ejection fraction (HFrEF), mean age 56±13 years, 89% male, 96% with coronary artery disease.
I
Intervention
Comprehensive outpatient cardiac rehabilitation program (centre-based or home-based/hybrid), 2-3 sessions per week combining multicomponent exercise with dietary guidance, health education, and psychosocial counselling.
O
Outcome
Change in 6-minute walk distance (6MWD), left ventricular ejection fraction (LVEF), and Physical/Mental component scores (PCS/MCS) of QoL upon CR completion.surrogate

Comprehensive outpatient cardiac rehabilitation significantly improves exercise capacity, cardiac function, and quality of life in heart failure patients in a developing country setting.

Cite This Study

Neelamegam et al. (2026) studied this question.

synapsesocial.com/papers/6a2bd1386550ea4541ffe97ahttps://doi.org/10.1093/eurjpc/zwag249.314
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Telehealth-Based Cardiac Rehabilitation for Heart Failure: A Systematic Review of Effectiveness, Access, and Patient-Centred Outcome2025
  2. 2Cardiac rehabilitation and health‐related quality of life in preserved ejection fraction heart failure: A meta‐analysis2025
  3. 3Cardiac rehabilitation in non-ischaemic cardiomyopathies: functional, psychosocial, and structural benefits compared with coronary artery disease2026
  4. 4Cardiac rehabilitation outcomes in heart failure: insights from echocardiographic deformation parameters2026
  5. 5Cardiac rehabilitation for workers with ischemic heart disease: Benefits for cardiovascular health and quality of life2025 · 1 citations