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September 10, 2025ESC Heart FailureOpen Access

Cardiac rehabilitation and health‐related quality of life in preserved ejection fraction heart failure: A meta‐analysis

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Authors

CDChao DingYGYawen GaoRTR Taylor

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Overview

Meta-analysis assesses exercise-based cardiac rehabilitation's impact on health-related quality of life in heart failure patients, highlighting significant improvements.

Key Points

  • Participation in exercise-based cardiac rehabilitation significantly improves health-related quality of life in patients with preserved ejection fraction heart failure.
  • Mean differences in HRQoL measures such as the Minnesota Living with Heart Failure Questionnaire indicate benefits of exercise interventions compared to controls.
  • This systematic review and meta-analysis involved twelve randomized controlled trials highlighting the heterogeneity in patient characteristics and intervention types.
  • The findings underscore the need for well-designed, fully powered trials to further confirm the positive health impacts of cardiac rehabilitation in this population.

Cite This Study

Ding et al. (2025) studied this question.

synapsesocial.com/papers/68c23b08b210217d64783836https://doi.org/10.1002/ehf2.15404
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Impact of Exercise Rehabilitation on Exercise Capacity and Quality-of-Life in Heart Failure2019 · 271 citations
  2. 2Exercise based cardiac rehabilitation for atrial fibrillation: Cochrane systematic review, meta-analysis, meta-regression and trial sequential analysis2025 · 13 citations
  3. 3Mediators of the effect of exercise-based cardiac rehabilitation on hospitalisation risk in people with coronary heart disease – the CaReMATCH individual participant data meta-analysis2026
  4. 4Effectiveness of comprehensive outpatient cardiac rehabilitation among heart failure patients in a developing country2026
  5. 5Impact of different exercise training modalities on patient-reported outcomes in heart failure with reduced and preserved ejection fraction2026