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December 8, 2025Blood

Trends and disparities in premature mortality from hematologic malignancies: Analysis of CDC wonder data, 1999-2020

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Authors

KPKara Piechowski

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Overview

Analysis reveals significant disparities in mortality rates from hematologic malignancies across racial and geographic groups, suggesting access issues.

Key Points

  • Mortality rates from hematologic malignancies substantially decreased among individuals under 55 from 1999 to 2020.
  • The overall age-adjusted mortality rate dropped from 3.7 to 1.9 per 100,000, with significant reductions across all demographic groups observed.
  • Joinpoint regression revealed varying trends among regions, notably with the Midwest seeing the steepest declines in mortality rates.
  • Persistent disparities based on race and urbanization highlight the need for improved access to modern therapies in underserved populations.

Cite This Study

Kara Piechowski (2025) studied this question.

synapsesocial.com/papers/69362f7f4fa91c937236e5d5https://doi.org/10.1182/blood-2025-8086
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Also Consider

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  1. 1Persistent and emerging racial gaps in mortality from malignant hematologic malignancies, 2018–20232025
  2. 2Trends in thromboembolism-related mortality among patients with hematologic malignancies in the u.S., 1999–2023: A CDC wonder analysis2025 · 1 citations
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  4. 4Aplastic anemia mortality in the United States (1999–2023): Trends, disparities, and public health implications2025
  5. 5Trends and disparities in hematologic malignancy and sepsis-related mortality in adults aged ≥ 65 years in the United States from 1999 to2023: A CDC wonder database analysis2025