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December 8, 2025Blood

Aplastic anemia mortality in the United States (1999–2023): Trends, disparities, and public health implications

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Authors

SKSaad KhanMMMadho MalYKYury Kachynski

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Overview

Retrospective analysis shows rising aplastic anemia mortality trends, indicating significant racial and demographic disparities in the US population over 24 years.

Key Points

  • Mortality rates for aplastic anemia show significant recent increases, with pronounced demographic disparities.
  • Age-adjusted mortality rates demonstrated a rising trend from 2015 to 2023, with males experiencing higher overall rates.
  • Utilizing a retrospective population-based analysis, mortality data were stratified by race, ethnicity, and geography.
  • Findings underscore the urgent need for equitable healthcare access to tackle disparities in aplastic anemia care.

Cite This Study

Khan et al. (2025) studied this question.

synapsesocial.com/papers/69362f604fa91c937236dd1dhttps://doi.org/10.1182/blood-2025-7996
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Temporal trends in aplastic anemia mortality across u.S. regions (1999–2020)2025
  2. 2Mortality patterns due to aplastic anemia in the United States: A retrospective analysis from 1999 to 20232025
  3. 3Aplastic anemia and substance use: National trends and associations in the United States from 1999-2023- a CDC wonder analysis2025
  4. 4The constant burden-aplastic anaemia as the underlying cause of death in older US adults- half century insights from the CDC wonder database (1968-2023)2025
  5. 5A dangerous convergence: Long-term mortality trends in aplastic anemia and sepsis (1999-2023)2025