December 8, 2025BloodOpen Access

Echocardiographic findings over time in sickle cell disease patients: A single-center study

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Patients with sickle cell disease showed increased echocardiographic signs of chamber dilation over time, especially those not on drug therapies.
Pulmonary artery systolic pressure changes were noted, with an increase in those receiving hydroxyurea compared to decreases with other drugs.
Analysis of echocardiograms from 36 sickle cell disease patients revealed critical cardiovascular concerns require further study.
Highlights the need for larger cohorts to establish significant relationships between disease-modifying drugs and echocardiographic findings.

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Implication

Retrospective analysis shows changes in echocardiographic findings in sickle cell disease patients, suggesting drug therapy impacts chamber dilation rate.

Cite This Study

Modupe Idowu (2025) studied this question.

synapsesocial.com/papers/69362f744fa91c937236e2da https://doi.org/10.1182/blood-2025-6504

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Implication

Retrospective analysis shows changes in echocardiographic findings in sickle cell disease patients, suggesting drug therapy impacts chamber dilation rate.

Echocardiographic findings over time in sickle cell disease patients: A single-center study

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Discussion

Implication

Cite This Study

Echocardiographic findings over time in sickle cell disease patients: A single-center study

Key Points

Discussion

Implication

Cite This Study

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