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December 8, 2025BloodOpen Access

Long-term projections of multiple myeloma mortality in the United States(2024-2040).: A time-series analysis stratified by sex, race, and geography

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Authors

AAAbdullah AhmadMAMeher AyyazuddinMNMohammad Nisar

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Overview

Time-series analysis forecasts decreasing mortality in multiple myeloma, highlighting gender, racial, and geographic disparities.

Key Points

  • Mortality rates for multiple myeloma are projected to decline by 28.0% from 4.07 in 2024 to 2.93 in 2040.
  • Gender disparities narrowed considerably, with males experiencing a decline of 68.6% compared to 30.8% for females.
  • Geographic analysis indicates that metro areas show a decline in mortality rates, while non-metro areas decline more slowly, widening their gap.
  • Forecasting trends through the ARIMA model underscores the importance of targeted interventions to address persistent disparities.

Cite This Study

Ahmad et al. (2025) studied this question.

synapsesocial.com/papers/69362f714fa91c937236e1d9https://doi.org/10.1182/blood-2025-7516
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Long-term survival, disparities, and future burden of multiple myeloma: A population-based analysis.2026
  2. 2Trends in mortality from multiple myeloma in patients younger than 55 years of age in the United States: A retrospective analysis from 1999 to 20202025
  3. 3Projected trends in ischemic heart disease mortality among patients with multiple myeloma in the United States: A forecast analysis through 2035.2026
  4. 4Temporal trends and demographic patterns in multiple myeloma incidence in the United States: a 24-year analysis of the CDC WONDER database (1999–2022)2026
  5. 5Temporal trends and demographic disparities in myelodysplastic syndrome-associated mortality in Acute Myeloid Leukemia patients in the United States: A population-based analysis (1999–2023)2025