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December 8, 2025Blood

Impact of sociodemographic factors on survival outcomes in chronic myeloid leukemia in the United States: A time-trend analysis

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Authors

RBRavi Bhatia

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Overview

Analysis shows improved survival in chronic myeloid leukemia across demographics, highlighting geographic variation and social determinants of health.

Key Points

  • Survival outcomes in chronic myeloid leukemia have significantly improved since 1999, particularly due to tyrosine kinase inhibitors.
  • Tyrosine kinase inhibitors have likely driven a notable decline in age-adjusted mortality-to-incidence ratios across all demographics.
  • Joinpoint regression analysis captured trends in CML incidence and mortality, revealing critical demographic and geographic disparities.
  • Disparities based on geography and age persist, indicating a need for addressing social determinants of health in treatment access.

Cite This Study

Ravi Bhatia (2025) studied this question.

synapsesocial.com/papers/69362f634fa91c937236de2chttps://doi.org/10.1182/blood-2025-6396
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