Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
December 8, 2025Blood

Improved outcomes in 17,908 acute myeloid leukemia patients across last three decades: Results from the multinational pethema registry

View Full Paper
Ask AI
Bookmark
Share

Authors

JMJosé MarizJBJuan Miguel Bergua BurguésMAMaría Luz Amigo

Discussion

Loading...

Member takes

Overview

Multinational analysis demonstrates improved overall survival in acute myeloid leukemia patients, suggesting evolving treatment strategies and supportive care.

Key Points

  • Median overall survival in acute myeloid leukemia improved from 9.3 to 12.8 months over three decades, highlighting therapeutic advancements.
  • Patients' baseline characteristics improved alongside a significant rise in the use of hypomethylating agents and targeted therapies.
  • Trends in treatment strategies, such as decreased reliance on intensive chemotherapy and increased use of allogeneic transplant, were observed.
  • Results indicate that ongoing improvements in treatment allocation may further enhance outcomes for acute myeloid leukemia patients.

Cite This Study

Mariz et al. (2025) studied this question.

synapsesocial.com/papers/69362f7f4fa91c937236e5f9https://doi.org/10.1182/blood-2025-40
View Full Paper
Ask AI
Bookmark
Share