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December 8, 2025BloodOpen Access

Disparities in venous thromboembolism management in patients with sickle cell disease: A nationwide inpatient sample study

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Authors

ASAshish Kumar SharmaATAngad Tiwari

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Overview

Observational analysis reveals significant racial disparities in treatment of venous thromboembolism among patients with sickle cell disease, suggesting a need for quality improvement initiatives.

Key Points

  • Hospitalized sickle cell disease patients face substantial disparities in venous thromboembolism treatment based on race.
  • African American patients showed reduced access to anticoagulation therapy, increasing their risk of in-hospital mortality.
  • Multivariable logistic regression was employed to analyze treatment patterns among hospitalized patients from 2019 to 2021.
  • The findings emphasize the importance of standardized treatment protocols to improve care equity for sickle cell patients.

Cite This Study

Sharma et al. (2025) studied this question.

synapsesocial.com/papers/69362f514fa91c937236d9bdhttps://doi.org/10.1182/blood-2025-2974
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Venous thromboembolism in adults with sickle cell disease: A national inpatient sample analysis (2016–2020)2025
  2. 2Racial and socioeconomic disparities in transfusion utilization among hospitalized sickle cell disease patients: An analysis of the 2022 national inpatient sample2025
  3. 3Venous thromboembolism and bleeding rates in pregnant and postpartum patients with sickle cell disease2025
  4. 4Closing the gap in vaso-occlusive episode triage for sickle cell patients: A quality improvement initiative2025
  5. 5Outcomes of long-term anticoagulation use in patients hospitalized with sickle cell vaso-occlusive crisis: A weighted analysis of the national inpatient sample (2016–2022)2025