Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
December 8, 2025BloodOpen Access

Incidence burden of AML across the US and Puerto Rico: A two-decade analysis of trends and disparities (1999-2021)

View Full Paper
Ask AI
Bookmark
Share

Authors

NANouman Aziz

Discussion

Loading...

Member takes

Overview

Population-based analysis reveals increasing AML incidence trends in various age groups, indicating health equity concerns.

Key Points

  • To evaluate and compare the incidence burden of AML across the United States and Puerto Rico, focusing on trends and disparities.
  • Retrospective population-based analysis using CDC Wonder Database
  • Calculated age-adjusted incidence rates (AAIRs) per 100,000 population
  • Utilized Joinpoint regression for trend analysis
  • Age-adjusted incidence rate of AML showed a modest increase with an AAPC of +0.49%
  • Significant increases observed in the South (AAPC: +0.76%) compared to other regions
  • Higher AAPC in females (+0.61%) than in males (+0.25%)
  • Adolescents (10-14) and older adults (85+) showed the highest increases in incidence

Cite This Study

Nouman Aziz (2025) studied this question.

synapsesocial.com/papers/693624d74fa91c937236d13dhttps://doi.org/10.1182/blood-2025-4435
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Changing burden of Acute Myeloid Leukemia in the United States: A 23-year national analysis2025
  2. 2Acute Myeloid Leukemia mortality in u.S. older adults: A 45-year nationwide analysis with forecasting through 20502025
  3. 3Comparative trends in mortality from acute lymphoblastic and Acute Myeloid Leukemia in the United States: A CDC wonder analysis (1999–2020)2025
  4. 4Impact of sociodemographic factors on survival outcomes in chronic myeloid leukemia in the United States: A time-trend analysis2025
  5. 5Temporal trends and demographic disparities in myelodysplastic syndrome-associated mortality in Acute Myeloid Leukemia patients in the United States: A population-based analysis (1999–2023)2025