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December 6, 2025Endocrine ConnectionsOpen Access

IUGR remodels glycogen synthesis in CG-IUGR rats

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CG-IUGR rats displayed significantly higher blood glucose levels post-glucose challenge, indicating glucose intolerance.
Serum insulin levels were lower while glucose tolerance tests showed increased blood glucose in CG-IUGR rats.
Established model using low-calorie diet during pregnancy to assess glucose metabolism changes across growth phases.
Findings may highlight the necessity for early interventions aimed at preventing diabetes in CG-IUGR individuals.

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Observational analysis found glucose intolerance and reduced insulin sensitivity in CG-IUGR rats, suggesting increased diabetes risk.

Liu et al. (2025) studied this question.

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