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December 4, 2025Journal of Viral HepatitisOpen Access

Modelling Micro‐Elimination: Third‐Trimester Tenofovir Prophylaxis for Perinatal Transmission of Hepatitis B in the Remote Dolpa District of Nepal

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Authors

BTBelaynew Wasie TayeSAShrestha Ananta

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Overview

Mathematical modelling shows third-trimester tenofovir reduces Hepatitis B prevalence in Dolpa, indicating micro-elimination is feasible by 2045.

Key Points

  • Elimination of Hepatitis B may be achievable by 2045 with improved third-trimester tenofovir.
  • Implementation of 90% TDF and high vaccination coverage could reduce HBV prevalence significantly.
  • This modelling approach examined the impact of various vaccination scenarios on HBV outcomes in Dolpa.
  • The findings support a targeted strategy for HBV control, highlighting micro-elimination in hard-to-reach areas.

Cite This Study

Taye et al. (2025) studied this question.

synapsesocial.com/papers/6930dc9eea1aef094cca2cabhttps://doi.org/10.1111/jvh.70110
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