The blocking efficacy and safety of tenofovir disoproxil fumarate tablets on mother-to-child transmission in pregnant women with high serum HBV DNA load: a retrospective cohort study
Retrospective cohort study shows tenofovir disoproxil fumarate improves safety and reduces mother-to-child transmission rates in infants born to mothers with high HBV DNA loads.
Key Points
This research aims to evaluate the blocking efficacy and safety of tenofovir disoproxil fumarate in preventing mother-to-child transmission of HBV.
Retrospective cohort study design
Evaluated pregnant women with high serum HBV DNA loads
Analyzed the efficacy and safety of tenofovir disoproxil fumarate tablets
Tenofovir disoproxil fumarate effectively prevents mother-to-child transmission of HBV
Treatment increased seroconversion rates of HBV DNA, HBeAg, and HBsAg in mothers and infants
The treatment demonstrated a favorable safety profile with no severe adverse outcomes