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September 10, 2025International Journal of STD & AIDS

Effectiveness of dolutegravir based antiretroviral treatment in preventing vertical transmission of HIV in West Bengal, India: A retrospective cohort study

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Authors

SGSuman GangulyDCDebjit ChakrabortyFDFalguni Debnath

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Overview

Retrospective cohort study shows dolutegravir regimen reduces HIV transmission in infants, suggesting improved outcomes in West Bengal.

Key Points

  • Dolutegravir-based ART reduced vertical HIV transmission rate to 2% compared to 6.5% with other regimens.
  • Study involved 1905 HIV-exposed infants, with 666 receiving dolutegravir and 1194 receiving efavirenz.
  • Retention of maternal antiretroviral therapy duration significantly correlated with lower transmission rates.
  • Effective infant feeding practices are crucial to further reduce the risk of mother to child HIV transmission.

Cite This Study

Ganguly et al. (2025) studied this question.

synapsesocial.com/papers/68c23fc3b210217d64797458https://doi.org/10.1177/09564624251361183
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