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December 4, 2025Clinical and Translational DiscoveryOpen Access

Mechanisms, impacts and therapeutic strategies of glucose metabolic reprogramming in tumours

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Authors

DSDan Song

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Overview

Review reveals glucose metabolism impacts metastasis and tumour growth in cancer, suggesting new diagnostic and therapeutic strategies.

Key Points

  • Targeting glucose metabolism may reduce tumour growth and metastasis, offering new cancer therapy avenues.
  • Key insights include the role of the Warburg effect and glycolytic enzymes in promoting immunosuppression.
  • Review systematically outlines molecular underpinnings of glucose metabolic reprogramming in tumours.
  • This approach highlights metabolic imaging as a potential tool for improved diagnosis and prognosis.

Cite This Study

Dan Song (2025) studied this question.

synapsesocial.com/papers/6930dc9eea1aef094cca2c2bhttps://doi.org/10.1002/ctd2.70100
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Molecular Mediators of Metabolic Reprogramming in Cancer: Mechanisms, Regulatory Networks, and Therapeutic Strategies2025
  2. 2Glucose metabolism and its direct action in cancer and immune regulation: opportunities and challenges for metabolic targeting2025
  3. 3Targeting the glycolytic switch in cancer: mechanisms, cancer progression and therapeutic challenges2025
  4. 4Glycolytic reprogramming in cancer: tumour cell metabolism, immune modulation, and therapeutic opportunities2026
  5. 5Glucose Metabolic Reprogramming in Colorectal Cancer: From Mechanisms to Targeted Therapy Approaches2025