October 15, 2025Access MicrobiologyOpen Access

Putative mutations associated with tetracycline resistance detected in Treponema spp.: an analysis of 4,355 Spirochaetales genomes

View Full Paper

Ask AI

Bookmark

Authors

Discussion

Analysis identifies tetracycline resistance mutations in Treponema and Spirochaeta species, suggesting implications for surveillance.

A transition mutation linked to tetracycline resistance was identified in 5.6% of Treponema spp. genomes.
Notable mutations in rpsC and rpsJ genes highlight the genetic mechanisms underlying antibiotic resistance.
Whole-genome sequencing of 4,355 genomes was utilized to analyze potential mutations associated with resistance.
Findings support the need for ongoing molecular surveillance to manage antibiotic resistance in STIs.

Manoharan-Basil et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark