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October 15, 2025American Journal of Food Science and TechnologyOpen Access

Evaluation of the Nutritional Profile and Obesogenic Potential of a Formulated High-Fat Diet

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Authors

EREdith ReubenBCBruno Chukwuemeka ChinkoNBNimisoere P. Batubo

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Overview

The study reveals how high-fat diets impact obesity metrics in male Wistar rats, indicating a strong dose-response relationship.

Key Points

  • High-fat diets significantly increased body weight by 35% in Wistar rats over 10 weeks.
  • The HF-20 diet showed the highest energy content at 4144.1 Kcal/kg, indicating enhanced feed efficiency.
  • Nutrient digestibility decreased alongside increased fat content, leading to notable changes in rat physiology.
  • The findings support the use of high-fat diets in exploring metabolic disorders and obesity in preclinical models.

Cite This Study

Reuben et al. (2025) studied this question.

synapsesocial.com/papers/68ef858cc6a308ba06355601https://doi.org/10.54536/ajfst.v4i2.5213
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  5. 5Switching from a High-Fat to a Regular Chow Diet Improves Obesity Progression in Mice2025