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October 12, 2025International Journal of Scientific Research in Science Engineering and TechnologyOpen Access

Synthesis, Characterisation, and Antimicrobial Evaluation of the Quinazoline-Thiazole Adducts

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Authors

SJSweta JoshiADA. M. DaveKSKinjal J. Sabalpara

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Overview

This research synthesizes quinazoline-thiazole adducts and evaluates their antimicrobial properties, indicating potential applications in drug development.

Key Points

  • Majority of synthesized quinazoline-thiazole adducts exhibited moderate antimicrobial activity against various microbial strains.
  • Compound 3a showcased antimicrobial potency comparable to a standard drug, highlighting its potential as a candidate for further development.
  • The synthesis involved a cyclisation reaction of hydrazine-carbothioamides and phenacyl bromides under mild conditions, confirming an effective approach.
  • Characterization of synthesized compounds utilized spectroscopic techniques, including 1H NMR, mass spectrometry, and IR spectroscopy.

Cite This Study

Joshi et al. (2025) studied this question.

synapsesocial.com/papers/68ebe3d6becc64ad52fdac11https://doi.org/10.32628/ijsrset251375
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  1. 1Exploring novel thiazolo[5,4-f]quinoline-based scaffolds as promising antimicrobial agents through synthesis and molecular insights2025 · 5 citations
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