Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 10, 2025Turkish Journal of Pharmaceutical SciencesOpen Access

Synthesis, Characterization, and Antimicrobial Evaluation of Some Novel Hydrazinecarbothioamides

View Full Paper
Ask AI
Bookmark
Share

Authors

EDEfe Doğukan DincelEKEbru Didem KuranHDHarika Öykü Dinç

Discussion

Loading...

Member takes

Overview

Novel thiosemicarbazide derivatives exhibit significant antimicrobial activity against several bacteria, suggesting potential for development.

Key Points

  • Five novel thiosemicarbazide derivatives display significant antimicrobial activity, particularly against S. aureus.
  • Compounds 5e and 5g recorded minimum inhibitory concentrations in the low micromolar range.
  • Synthesis involved reacting 1,2,4-triazole derivatives with thiosemicarbazide, characterized by NMR and infrared spectroscopy.
  • These derivatives could be developed into potent antimicrobial agents, meriting further exploration of their mechanisms.

Cite This Study

Dincel et al. (2025) studied this question.

synapsesocial.com/papers/68c23caeb210217d6478aaa6https://doi.org/10.4274/tjps.galenos.2025.90304
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1New 4-(Morpholin-4-Yl)-3-Nitrobenzhydrazide Based Scaffold: Synthesis, Structural Insights, and Biological Evaluation2025
  2. 2Synthesis and Antimicrobial Efficacy of Novel 1,3,4-Thiadiazole Derivatives Against Key Bacterial and Fungal Strains2025
  3. 3Fluorophenyl-1,2,4-Triazole Derivatives: Synthesis, Structural Analysis, Chemotype Clustering and Antimicrobial Screening2025 · 1 citations
  4. 4Synthesis, Characterisation, and Antimicrobial Evaluation of the Quinazoline-Thiazole Adducts2025
  5. 5Synthesis, Antimicrobial and Antioxidant Activity With ADMET Prediction, Molecular Docking, and Dynamics Studies of Novel Thiazole‐Schiff Base Derivatives2025 · 2 citations